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Glyoxalase I activity and immunoreactivity in the aging human lens

Glyoxalase I (GLOI) is the first enzyme of the glyoxalase system that catalyzes the metabolism of reactive dicarbonyls, such as methylglyoxal (MGO). During aging and cataract development, human lens proteins are chemically modified by MGO, which is likely due to inadequate metabolism of MGO by the g...

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Autors principals: Mailankot, Maneesh, Padmanabha, Smitha, Pasupuleti, NagaRekha, Major, Denice, Howell, Scott, Nagaraj, Ram H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560407/
https://ncbi.nlm.nih.gov/pubmed/19238574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-009-9218-2
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