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Glyoxalase I activity and immunoreactivity in the aging human lens

Glyoxalase I (GLOI) is the first enzyme of the glyoxalase system that catalyzes the metabolism of reactive dicarbonyls, such as methylglyoxal (MGO). During aging and cataract development, human lens proteins are chemically modified by MGO, which is likely due to inadequate metabolism of MGO by the g...

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Main Authors: Mailankot, Maneesh, Padmanabha, Smitha, Pasupuleti, NagaRekha, Major, Denice, Howell, Scott, Nagaraj, Ram H.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560407/
https://ncbi.nlm.nih.gov/pubmed/19238574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-009-9218-2
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