Oxidative Post-Translational Modifications Mediate Decreased SERCA Activity and Myocyte Dysfunction in Gαq-Overexpressing Mice

BACKGROUND: Myocyte contractile dysfunction occurs in pathological remodeling in association with abnormalities in calcium regulation. Mice with cardiac myocyte-specific overexpression of Gαq develop progressive left ventricular (LV) failure associated with myocyte contractile dysfunction and calciu...

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Detalhes bibliográficos
Main Authors: Lancel, Steve, Qin, Fuzhong, Lennon, Shannon L., Zhang, Jingmei, Tong, XiaoYong, Mazzini, Michael J., Kang, Y. James, Siwik, Deborah A, Cohen, Richard A., Colucci, Wilson S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909347/
https://ncbi.nlm.nih.gov/pubmed/20508180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.217570
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