Cardiac-specific overexpression of catalase identifies hydrogen peroxide-dependent and independent-phases of myocardial remodeling, and prevents the progression to overt heart failure in Gαq-overexpressing transgenic mice

BACKGROUND: While it appears that reactive oxygen species (ROS) contribute to chronic myocardial remodeling, questions remain about a) the specific type(s) of ROS involved, b) the role of ROS in mediating specific cellular events, and c) the cause and effect relationship between myocardial ROS and t...

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Main Authors: Qin, Fuzhong, Lennon-Edwards, Shannon, Lancel, Steve, Biolo, Andreia, Siwik, Deborah A., Pimentel, David R., Dorn, Gerald W., Kang, Y. James, Colucci, Wilson S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062519/
https://ncbi.nlm.nih.gov/pubmed/20018955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.864785
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