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Specific binding of photoaffinity-labeling peptidomimetics of Pro-Leu-Gly-NH(2) to the dopamine D(2L) receptor: Evidence for the allosteric modulation of the dopamine receptor
The present study was undertaken to investigate the mechanistic role of L-prolyl-L-leucyl-glycinamide (PLG) in modulating agonist binding to the dopamine D(2L) receptor. Competition and displacement assays indicate that the photoaffinity-labeling peptidomimetics of PLG, 3(R)-[(4(S)-(4-azido-2-hydrox...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907365/ https://ncbi.nlm.nih.gov/pubmed/20639138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.05.018 |
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