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Development of peptidomimetic ligands of Pro-Leu-Gly-NH(2) as allosteric modulators of the dopamine D(2) receptor

A variety of stable, small-molecule peptidomimetic ligands have been developed to elucidate the mechanism by which the neuropeptide Pro-Leu-Gly-NH(2) (PLG) modulates dopaminergic neurotransmission. Photoaffinity labeling ligands based upon PLG peptidomimetics have been used to establish that PLG bin...

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Detalhes bibliográficos
Main Authors: Bhagwanth, Swapna, Mishra, Ram K, Johnson, Rodney L
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566759/
https://ncbi.nlm.nih.gov/pubmed/23400263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.24
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