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Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH(2)
A peptidomimetic of Pro-Leu-Pro-NH(2), 7, possessing an indolizidinone type VI β-turn mimic was synthesized via improved high-yielding protocols for the preparation and Cbz-protection of α-allyl proline. Bicyclic peptidomimetic 7 and spirobicylic peptidomimetic 8 enhanced the binding of [(3)H]N-prop...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529021/ https://ncbi.nlm.nih.gov/pubmed/18052024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070895r |
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