Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction

Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/∆KPQ mice modeling long QT3 syndrome in relationship to cardiac Na(+) channel, Nav1.5, expression. Atrial e...

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Bibliographic Details
Main Authors: Guzadhur, Laila, Pearcey, Sarah M., Duehmke, Rudolf M., Jeevaratnam, Kamalan, Hohmann, Anja F., Zhang, Yanmin, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2010
Subjects:
Cardiovascular Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903684/
https://ncbi.nlm.nih.gov/pubmed/20552221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0851-z
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