Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction

Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/∆KPQ mice modeling long QT3 syndrome in relationship to cardiac Na(+) channel, Nav1.5, expression. Atrial e...

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Autori principali: Guzadhur, Laila, Pearcey, Sarah M., Duehmke, Rudolf M., Jeevaratnam, Kamalan, Hohmann, Anja F., Zhang, Yanmin, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
Soggetti:
Cardiovascular Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903684/
https://ncbi.nlm.nih.gov/pubmed/20552221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0851-z
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