Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a(+/ΔKPQ) Mice

Circadian rhythms are generated by cell autonomous circadian clocks that perform a ubiquitous cellular time-keeping function and cell type-specific functions important for normal physiology. Studies show inducing the deletion of the core circadian clock transcription factor Bmal1 in adult mouse card...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Schroder, Elizabeth A., Wayland, Jennifer L., Samuels, Kaitlyn M., Shah, Syed F., Burgess, Don E., Seward, Tanya, Elayi, Claude S., Esser, Karyn A., Delisle, Brian P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265216/
https://ncbi.nlm.nih.gov/pubmed/34248669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.681011
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