Delayed conduction and its implications in murine Scn5a(+/−) hearts: independent and interacting effects of genotype, age, and sex

We explored for relationships between SCN5A haploinsufficiency, implicated in clinical arrhythmogenicity, and right ventricular (RV) conduction disorders in Langendorff-perfused, male and female, and young (3 months) and old (>12 month old) Scn5a (+/−) and wild type (WT) hearts. The investigated...

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Hlavní autoři: Jeevaratnam, Kamalan, Poh Tee, Sui, Zhang, Yanmin, Rewbury, Rebecca, Guzadhur, Laila, Duehmke, Rudolf, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2010
Témata:
Cardiovascular Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016216/
https://ncbi.nlm.nih.gov/pubmed/21127902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0906-1
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