Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction

Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/∆KPQ mice modeling long QT3 syndrome in relationship to cardiac Na(+) channel, Nav1.5, expression. Atrial e...

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Autors principals: Guzadhur, Laila, Pearcey, Sarah M., Duehmke, Rudolf M., Jeevaratnam, Kamalan, Hohmann, Anja F., Zhang, Yanmin, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2010
Matèries:
Cardiovascular Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903684/
https://ncbi.nlm.nih.gov/pubmed/20552221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0851-z
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