Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction

Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/∆KPQ mice modeling long QT3 syndrome in relationship to cardiac Na(+) channel, Nav1.5, expression. Atrial e...

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Detalhes bibliográficos
Main Authors: Guzadhur, Laila, Pearcey, Sarah M., Duehmke, Rudolf M., Jeevaratnam, Kamalan, Hohmann, Anja F., Zhang, Yanmin, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Cardiovascular Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903684/
https://ncbi.nlm.nih.gov/pubmed/20552221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0851-z
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