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C Terminus of Nucleotide Binding Domain 1 Contains Critical Features for Cystic Fibrosis Transmembrane Conductance Regulator Trafficking and Activation
The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl(−) channel physiologically important in fluid-transporting epithelia and pathologically relevant in several human diseases. Here, we show that mutations in the C terminus of the first nucleotide binding domain comprising the late...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903390/ https://ncbi.nlm.nih.gov/pubmed/20435887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.120683 |
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