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Role of Tyrosine Phosphorylation in the Muscarinic Activation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride (Cl(−)) channel, which plays an important role in physiological anion and fluid secretion, and is defective in several diseases. Although its activation by PKA and PKC has been studied extensively, its regulation by receptors i...

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Bibliographic Details
Main Authors: Billet, Arnaud, Luo, Yishan, Balghi, Haouaria, Hanrahan, John W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724638/
https://ncbi.nlm.nih.gov/pubmed/23760269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479360
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