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Role of Tyrosine Phosphorylation in the Muscarinic Activation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride (Cl(−)) channel, which plays an important role in physiological anion and fluid secretion, and is defective in several diseases. Although its activation by PKA and PKC has been studied extensively, its regulation by receptors i...

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Hlavní autoři: Billet, Arnaud, Luo, Yishan, Balghi, Haouaria, Hanrahan, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724638/
https://ncbi.nlm.nih.gov/pubmed/23760269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479360
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