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How Phosphorylation and ATPase Activity Regulate Anion Flux though the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

The cystic fibrosis transmembrane conductance regulator (CFTR, ABCC7), mutations of which cause cystic fibrosis, belongs to the ATP-binding cassette (ABC) transporter family and works as a channel for small anions, such as chloride and bicarbonate. Anion channel activity is known to depend on phosph...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Zwick, Matthias, Esposito, Cinzia, Hellstern, Manuel, Seelig, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938172/
https://ncbi.nlm.nih.gov/pubmed/27226582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721415
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