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Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Understanding the functional consequence of rare cystic fibrosis (CF) mutations is mandatory for the adoption of precision therapeutic approaches for CF. Here we studied the effect of the very rare CF mutation, W361R, on CFTR processing and function. We applied western blot, patch clamp and pharmaco...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Billet, Arnaud, Elbahnsi, Ahmad, Jollivet-Souchet, Mathilde, Hoffmann, Brice, Mornon, Jean-Paul, Callebaut, Isabelle, Becq, Frédéric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092619/
https://ncbi.nlm.nih.gov/pubmed/32256364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00295
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