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Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Understanding the functional consequence of rare cystic fibrosis (CF) mutations is mandatory for the adoption of precision therapeutic approaches for CF. Here we studied the effect of the very rare CF mutation, W361R, on CFTR processing and function. We applied western blot, patch clamp and pharmaco...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Billet, Arnaud, Elbahnsi, Ahmad, Jollivet-Souchet, Mathilde, Hoffmann, Brice, Mornon, Jean-Paul, Callebaut, Isabelle, Becq, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092619/
https://ncbi.nlm.nih.gov/pubmed/32256364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00295
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