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Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Understanding the functional consequence of rare cystic fibrosis (CF) mutations is mandatory for the adoption of precision therapeutic approaches for CF. Here we studied the effect of the very rare CF mutation, W361R, on CFTR processing and function. We applied western blot, patch clamp and pharmaco...

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Foilsithe in:Front Pharmacol
Main Authors: Billet, Arnaud, Elbahnsi, Ahmad, Jollivet-Souchet, Mathilde, Hoffmann, Brice, Mornon, Jean-Paul, Callebaut, Isabelle, Becq, Frédéric
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092619/
https://ncbi.nlm.nih.gov/pubmed/32256364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00295
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