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Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function
The chloride (Cl(-)) channel cystic fibrosis transmembrane conductance regulator (CFTR) is defective in cystic fibrosis (CF), and mutation of its encoding gene leads to various defects such as retention of the misfolded protein in the endoplasmic reticulum, reduced stability at the plasma membrane,...
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Pubblicato in: | Front Pharmacol |
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Autori principali: | , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Frontiers Media S.A.
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5383655/ https://ncbi.nlm.nih.gov/pubmed/28439239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00195 |
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