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Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function

The chloride (Cl(-)) channel cystic fibrosis transmembrane conductance regulator (CFTR) is defective in cystic fibrosis (CF), and mutation of its encoding gene leads to various defects such as retention of the misfolded protein in the endoplasmic reticulum, reduced stability at the plasma membrane,...

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Publicat a:Front Pharmacol
Autors principals: Billet, Arnaud, Froux, Lionel, Hanrahan, John W., Becq, Frederic
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383655/
https://ncbi.nlm.nih.gov/pubmed/28439239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00195
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