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Phosphatase inhibitors activate normal and defective CFTR chloride channels.

The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is regulated by phosphorylation and dephosphorylation at multiple sites. Although activation by protein kinases has been studied in some detail, the dephosphorylation step has received little attention. This report exami...

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Detalhes bibliográficos
Main Authors: Becq, F, Jensen, T J, Chang, X B, Savoia, A, Rommens, J M, Tsui, L C, Buchwald, M, Riordan, J R, Hanrahan, J W
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44767/
https://ncbi.nlm.nih.gov/pubmed/7522329
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