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The secret life of CFTR as a calcium-activated chloride channel

cAMP-stimulated anion conductance is defective in cystic fibrosis (CF). The regulatory domain of CFTR, the anion channel protein encoded by the CF gene, possesses an unusually high density of consensus sequences for phosphorylation by protein kinase A (14 in a stretch of <200 amino acids). Thus i...

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Detalhes bibliográficos
Main Authors: Billet, Arnaud, Hanrahan, John W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936366/
https://ncbi.nlm.nih.gov/pubmed/23959675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.261909
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