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Structural basis for specificity and potency of xanthine derivatives as activators of the CFTR chloride channel
1. On the basis of their structure, we compared the ability of 35 xanthine derivatives to activate the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel stably expressed in chinese hamster ovary (CHO) cells using the cell-attached patch clamp and iodide efflux techniques. 2...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1998
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565206/ https://ncbi.nlm.nih.gov/pubmed/9517388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701648 |
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