Identification of an ion channel-forming motif in the primary structure of CFTR, the cystic fibrosis chloride channel.

Synthetic peptides with sequences representing putative transmembrane (M) segments of CFTR (the cystic fibrosis transmembrane conductance regulator) were used as tools to identify the involvement of such segments in forming the ionic pore of the CFTR Cl- channel. Peptides with sequences correspondin...

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Autores principales: Oblatt-Montal, M, Reddy, G L, Iwamoto, T, Tomich, J M, Montal, M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC43186/
https://ncbi.nlm.nih.gov/pubmed/7509074
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