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Identification of an ion channel-forming motif in the primary structure of CFTR, the cystic fibrosis chloride channel.

Synthetic peptides with sequences representing putative transmembrane (M) segments of CFTR (the cystic fibrosis transmembrane conductance regulator) were used as tools to identify the involvement of such segments in forming the ionic pore of the CFTR Cl- channel. Peptides with sequences correspondin...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Oblatt-Montal, M, Reddy, G L, Iwamoto, T, Tomich, J M, Montal, M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1495
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