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Identification of an ion channel-forming motif in the primary structure of CFTR, the cystic fibrosis chloride channel.

Synthetic peptides with sequences representing putative transmembrane (M) segments of CFTR (the cystic fibrosis transmembrane conductance regulator) were used as tools to identify the involvement of such segments in forming the ionic pore of the CFTR Cl- channel. Peptides with sequences correspondin...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Oblatt-Montal, M, Reddy, G L, Iwamoto, T, Tomich, J M, Montal, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1495
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