Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel.

Cystic fibrosis transmembrane conductance regulator (CFTR) generates cAMP-regulated Cl- channels; mutations in CFTR cause defective Cl- channel function in cystic fibrosis epithelia. We used the patch-clamp technique to determine the single channel properties of Cl- channels in cell expressing recom...

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Pubblicato in:	J Clin Invest
Autori principali:	Berger, H A, Anderson, M P, Gregory, R J, Thompson, S, Howard, P W, Maurer, R A, Mulligan, R, Smith, A E, Welsh, M J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295615/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115450
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