Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel.

Cystic fibrosis transmembrane conductance regulator (CFTR) generates cAMP-regulated Cl- channels; mutations in CFTR cause defective Cl- channel function in cystic fibrosis epithelia. We used the patch-clamp technique to determine the single channel properties of Cl- channels in cell expressing recom...

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Autors principals: Berger, H A, Anderson, M P, Gregory, R J, Thompson, S, Howard, P W, Maurer, R A, Mulligan, R, Smith, A E, Welsh, M J
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295615/
https://ncbi.nlm.nih.gov/pubmed/1717515
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