Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator

CFTR is a cyclic AMP (cAMP)-activated chloride (Cl(−)) channel and a regulator of outwardly rectifying Cl(−) channels (ORCCs) in airway epithelia. CFTR regulates ORCCs by facilitating the release of ATP out of cells. Once released from cells, ATP stimulates ORCCs by means of a purinergic receptor. T...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Schwiebert, Erik M., Morales, Marcelo M., Devidas, Sreenivas, Egan, Marie E., Guggino, William B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2674
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