Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator

CFTR is a cyclic AMP (cAMP)-activated chloride (Cl(−)) channel and a regulator of outwardly rectifying Cl(−) channels (ORCCs) in airway epithelia. CFTR regulates ORCCs by facilitating the release of ATP out of cells. Once released from cells, ATP stimulates ORCCs by means of a purinergic receptor. T...

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Egile Nagusiak: Schwiebert, Erik M., Morales, Marcelo M., Devidas, Sreenivas, Egan, Marie E., Guggino, William B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1998
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC19458/
https://ncbi.nlm.nih.gov/pubmed/9482946
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