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Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore

Different transmembrane (TM) α helices are known to line the pore of the cystic fibrosis TM conductance regulator (CFTR) Cl(−) channel. However, the relative alignment of these TMs in the three-dimensional structure of the pore is not known. We have used patch-clamp recording to investigate the acce...

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Hlavní autoři: Wang, Wuyang, El Hiani, Yassine, Linsdell, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149817/
https://ncbi.nlm.nih.gov/pubmed/21746847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110605
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