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Changes in Accessibility of Cytoplasmic Substances to the Pore Associated with Activation of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
Opening of the cystic fibrosis transmembrane conductance regulator Cl(−) channel is dependent both on phosphorylation and on ATP binding and hydrolysis. However, the mechanisms by which these cytoplasmic regulatory factors open the Cl(−) channel pore are not known. We have used patch clamp recording...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952214/ https://ncbi.nlm.nih.gov/pubmed/20675380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113332 |
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