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Metal Bridges Illuminate Transmembrane Domain Movements during Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel

Opening and closing of the cystic fibrosis transmembrane conductance regulator are controlled by ATP binding and hydrolysis by the cytoplasmic nucleotide-binding domains. Different conformational changes in the channel pore have been described during channel opening and closing; however, the relativ...

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Detalhes bibliográficos
Main Authors: El Hiani, Yassine, Linsdell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192471/
https://ncbi.nlm.nih.gov/pubmed/25143385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.593103
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