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Metal Bridges Illuminate Transmembrane Domain Movements during Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel

Opening and closing of the cystic fibrosis transmembrane conductance regulator are controlled by ATP binding and hydrolysis by the cytoplasmic nucleotide-binding domains. Different conformational changes in the channel pore have been described during channel opening and closing; however, the relativ...

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Bibliografske podrobnosti
Main Authors: El Hiani, Yassine, Linsdell, Paul
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192471/
https://ncbi.nlm.nih.gov/pubmed/25143385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.593103
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