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Functional organization of cytoplasmic portals controlling access to the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel pore
The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl(−) channel that apparently has evolved from an ancestral active transporter. Key to the CFTR's switch from pump to channel function may have been the appearance of one or more “lateral portals.” Such portals connect the cyto...
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| Published in: | J Biol Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5900759/ https://ncbi.nlm.nih.gov/pubmed/29475947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001373 |
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