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Taxol biosynthesis and molecular genetics
Biosynthesis of the anticancer drug Taxol in Taxus (yew) species involves 19 steps from the universal diterpenoid progenitor geranylgeranyl diphosphate derived by the plastidial methyl erythritol phosphate pathway for isoprenoid precursor supply. Following the committed cyclization to the taxane ske...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901146/ https://ncbi.nlm.nih.gov/pubmed/20622989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11101-005-3748-2 |
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