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Cytochrome P450 oxygenases of Taxol biosynthesis

Cytochrome P450 monooxygenases play a prominent role in the biosynthesis of the diterpenoid anticancer drug Taxol, as they appear to constitute about half of the 19 enzymatic steps of the pathway in yew (Taxus) species. A combination of classical biochemical and molecular methods, including cell-fre...

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Detalhes bibliográficos
Main Authors: Kaspera, Rüdiger, Croteau, Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901147/
https://ncbi.nlm.nih.gov/pubmed/20622990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11101-006-9006-4
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