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Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase
A central feature in the biosynthesis of Taxol is oxygenation at multiple positions of the taxane core structure, reactions that are considered to be mediated by cytochrome P450-dependent monooxygenases. A PCR-based differential display-cloning approach, using Taxus (yew) cells induced for Taxol pro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC61086/ https://ncbi.nlm.nih.gov/pubmed/11707604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251539398 |
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