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Taxol biosynthesis and molecular genetics

Biosynthesis of the anticancer drug Taxol in Taxus (yew) species involves 19 steps from the universal diterpenoid progenitor geranylgeranyl diphosphate derived by the plastidial methyl erythritol phosphate pathway for isoprenoid precursor supply. Following the committed cyclization to the taxane ske...

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Bibliografiska uppgifter
Huvudupphovsmän: Croteau, Rodney, Ketchum, Raymond E. B., Long, Robert M., Kaspera, Rüdiger, Wildung, Mark R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901146/
https://ncbi.nlm.nih.gov/pubmed/20622989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11101-005-3748-2
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