Synchronization in G(0)/G(1) enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin

Evaluating mitogenic signaling specifically through the human insulin receptor (IR) is relevant for the preclinical safety assessment of developmental insulin analogs. It is known that overexpression of IR sensitizes cells to the mitogenic effects of insulin, but it is essentially unknown how mitoge...

Full description

Saved in:
Bibliographic Details
Main Authors: Bonnesen, Christine, Nelander, Gitte-Mai, Hansen, Bo Falck, Jensen, Pia, Krabbe, Jonas S., Jensen, Marianne B., Hegelund, Anne Charlotte, Svendsen, Jette E., Oleksiewicz, Martin B.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896650/
https://ncbi.nlm.nih.gov/pubmed/19898946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-009-9142-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items