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Synchronization in G(0)/G(1) enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin
Evaluating mitogenic signaling specifically through the human insulin receptor (IR) is relevant for the preclinical safety assessment of developmental insulin analogs. It is known that overexpression of IR sensitizes cells to the mitogenic effects of insulin, but it is essentially unknown how mitoge...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896650/ https://ncbi.nlm.nih.gov/pubmed/19898946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-009-9142-x |
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