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Synchronization in G(0)/G(1) enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin

Evaluating mitogenic signaling specifically through the human insulin receptor (IR) is relevant for the preclinical safety assessment of developmental insulin analogs. It is known that overexpression of IR sensitizes cells to the mitogenic effects of insulin, but it is essentially unknown how mitoge...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bonnesen, Christine, Nelander, Gitte-Mai, Hansen, Bo Falck, Jensen, Pia, Krabbe, Jonas S., Jensen, Marianne B., Hegelund, Anne Charlotte, Svendsen, Jette E., Oleksiewicz, Martin B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896650/
https://ncbi.nlm.nih.gov/pubmed/19898946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-009-9142-x
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