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Interleukin-1β Promotes Gastric Atrophy Through Suppression of Sonic Hedgehog
BACKGROUND & AIMS: In both human subjects and rodent models, Helicobacter infection leads to a decrease in Shh expression in the stomach. Sonic Hedgehog (Shh) is highly expressed in the gastric corpus and its loss correlates with gastric atrophy. Therefore, we tested the hypothesis that proinfla...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895809/ https://ncbi.nlm.nih.gov/pubmed/19883649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.10.043 |
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