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Sonic Hedgehog in Gastric Physiology and Neoplastic Transformation: Friend or Foe?

PURPOSE OF REVIEW: To understand the role of sonic hedgehog (Shh) in normal gastric physiology and neoplastic transformation. RECENT FINDINGS: Emerging evidence shows that gastric epithelial cells produce Shh ligand, which subsequently targets the mesenchyme. This paracrine signaling event is recapi...

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Detalhes bibliográficos
Main Authors: El-Zaatari, Mohamad, Saqui-Salces, Milena, Waghray, Megna, Todisco, Andrea, Merchant, Juanita L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895804/
https://ncbi.nlm.nih.gov/pubmed/19104239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MED.0b013e328320a821
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