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Inhibition of Hedgehog Signaling in the Gastrointestinal Tract: Targeting the Cancer Microenvironment
This review summarizes emerging information regarding the Hedgehog (Hh) signaling pathway during neoplastic transformation in the gastrointestinal tract. Although there is a role for the well-established canonical pathway in which Hedgehog ligands interact with their receptor Patched, there is suffi...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823758/ https://ncbi.nlm.nih.gov/pubmed/24007940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2013.08.003 |
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