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Hedgehog signaling and gastrointestinal cancer

Hedgehog (Hh) signaling is critical for embryonic development and in differentiation, proliferation, and maintenance of multiple adult tissues. De-regulation of the Hh pathway is associated with birth defects and cancer. In the gastrointestinal tract, Hh ligands Sonic (Shh) and Indian (Ihh), as well...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Saqui-Salces, Milena, Merchant, Juanita L.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340308/
https://ncbi.nlm.nih.gov/pubmed/20307590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.03.008
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