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Mutagenesis and Evolution of Sulfated Antibodies using an Expanded Genetic Code

To facilitate the biochemical study of posttranslationally modified proteins, we have developed a strategy in which otherwise posttranslationally modified amino acids are genetically encoded in E. coli in response to unique nonsense or frameshift codons. Here, we illustrate the utility of this appro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Chang C., Choe, Hyeryun, Farzan, Michael, Smider, Vaughn V., Schultz, Peter G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891052/
https://ncbi.nlm.nih.gov/pubmed/19715291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9011429
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