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Nonspecific DNA binding activity of simian virus 40 large T antigen: evidence for the cooperation of two regions for full activity.

We generated a series of COOH-terminal truncated simian virus 40 large tumor (T) antigens by using oligonucleotide-directed site-specific mutagenesis. The mutant proteins [T(1-650) to T(1-516)] were expressed in insect cells infected with recombinant baculoviruses. T(1-623) and shorter proteins [T(1...

詳細記述

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書誌詳細
主要な著者: Lin, H J, Upson, R H, Simmons, D T
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC289101/
https://ncbi.nlm.nih.gov/pubmed/1323705
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