Nonspecific DNA binding activity of simian virus 40 large T antigen: evidence for the cooperation of two regions for full activity.

We generated a series of COOH-terminal truncated simian virus 40 large tumor (T) antigens by using oligonucleotide-directed site-specific mutagenesis. The mutant proteins [T(1-650) to T(1-516)] were expressed in insect cells infected with recombinant baculoviruses. T(1-623) and shorter proteins [T(1...

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Publicat a:	J Virol
Autors principals:	Lin, H J, Upson, R H, Simmons, D T
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289101/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5443-5452.1992
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