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Role of Single-Stranded DNA Binding Activity of T Antigen in Simian Virus 40 DNA Replication

We have previously mapped the single-stranded DNA binding domain of large T antigen to amino acid residues 259 to 627. By using internal deletion mutants, we show that this domain most likely begins after residue 301 and that the region between residues 501 and 550 is not required. To study the func...

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Autori principali: Wu, Chunxiao, Roy, Rupa, Simmons, Daniel T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC115910/
https://ncbi.nlm.nih.gov/pubmed/11222709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2839-2847.2001
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