Sequence Requirements for the Assembly of Simian Virus 40 T Antigen and the T-Antigen Origin Binding Domain on the Viral Core Origin of Replication

The regions of the simian virus 40 (SV40) core origin that are required for stable assembly of virally encoded T antigen (T-ag) and the T-ag origin binding domain (T-ag-obd(131–260)) have been determined. Binding of the purified T-ag-obd(131–260) is mediated by interactions with the central region o...

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Main Authors: Kim, Henry Y., Barbaro, Brett A., Joo, Woo S., Prack, Andrea E., Sreekumar, K. R., Bullock, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104281/
https://ncbi.nlm.nih.gov/pubmed/10438844
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