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Topoisomerase I Associates Specifically with Simian Virus 40 Large-T-Antigen Double Hexamer–Origin Complexes

Topoisomerase I (topo I) is required for releasing torsional stress during simian virus 40 (SV40) DNA replication. Recently, it has been demonstrated that topo I participates in initiation of replication as well as in elongation. Although T antigen and topo I can bind to one another in vitro, there...

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Bibliografische gegevens
Hoofdauteurs: Gai, Dahai, Roy, Rupa, Wu, Chunxiao, Simmons, Daniel T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110876/
https://ncbi.nlm.nih.gov/pubmed/10799598
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